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Many Americans taking the blockbuster drug Ozempic have ‘no desire’ to drink, have stopped gambling, and find themselves no longer interested in their favorite foods.

It’s well-established that Ozempic, an injectable medication approved for diabetes, has helped millions of Americans lose weight by reducing their appetite and cravings for unhealthy foods. 

However, a growing body of research suggests its active ingredient, semaglutide, could also curb appetites for alcohol, nicotine, nail-biting, and even gambling. 

Users told DailyMail.com they have stopped wanting to consume alcohol, which made them feel better after a night out, and it has made them ‘excited’ to see what other habits Ozempic may change.

They also said it could be a game-changer for alcoholics and those struggling with other addictions.

Ozempic users have previously told DailyMail.com the drug has caused them to no longer crave alcohol

Ozempic and its sister drug Wegovy work by triggering the body to bind to a receptor called the glucagon-like peptide-1 (GLP-1), a protein that triggers hormones in the brain that keep the stomach full and tell the body to stop eating and avoid cravings

Karen Ramirez, 32, a high school teacher from Rhode Island, started taking Ozempic in February for polycystic ovary syndrome (PCOS).

PCOS is a hormonal disorder that affects one in 10 American women of childbearing age, according to the US Office on Women’s Health. It causes the ovaries to produce excessive amounts of the male sex hormones. This leads to irregular menstrual cycles, abnormal hair growth, acne, obesity, thinning hair, and infertility. 

Ms Ramirez told DailyMail.com: ‘I always had really inconsistent periods. Sometimes, I would go months without having a period, which is obviously not normal, even though I wouldn’t be pregnant or anything like that.’  

While she was pregnant two years ago, she developed gestational diabetes, which is diagnosed in pregnant women who aren’t already diabetic. She was also constantly hungry and unable to lose weight.

Doctors put Ms Ramirez on Ozempic to help balance her hormones earlier this year. 

Since then, she has lost about 20 pounds and stopped snacking. She also has no desire to drink alcohol.

‘I’ve never been a drinker. I’ve always been a social drinker. I’ll have a glass of wine, or I’ll have some beer…but now I do not even want to try it at all,’ she said. 

‘It kind of grosses me out, to be honest.’ 

Before Ozempic, Ms Ramirez would have no more than three drinks at a social event. Now, she barely wants to order one.

‘I don’t really see the need to have wine or have a beer, and if I do, I’ll have one glass,’ she said. 

She’s far from alone. 

A TikTok user who goes by myshellk said in a video: ‘Since being on Ozempic, I have no desire to drink.’

She also said these effects could be helpful for those struggling with alcoholism. 

‘That would be really cool if someone who needs that can have access,’ she said. 

‘I’m excited to see what other cool things [Ozempic] will have an effect on.’

One of the other effects could be a loss of interest in a user’s favorite foods. Staci Rice, 40, who reports taking semaglutide said her favorite chocolate candy, Kit Kats, are now repulsive to her. 

Mel, (left) who goes by the username Cgo_of_me on TikTok, shared she recently went out for two martinis while taking Ozempic. She woke up feeling ‘violently, violently sick.’ ‘From now on, I won’t be drinking. Neither should you,’ she said. Karen Ramirez (right) posted on TikTok and told DailyMail.com that Ozempic made her ‘disgusted’ by alcohol

Staci Rice (pictured), 40, said that she can no longer stomach coffee or Kit-Kats after using Wegovy

Another TikTok user named christienano said she can no longer drink red wine, her beverage of choice. However, she insisted, ‘that’s not a bad thing.’

‘You absolutely lose your craving for alcohol, and that really helps in weight loss as well,’ she said. 

Ozempic is a brand name for the medication semaglutide, which suppresses appetite and triggers weight loss.

The drug binds to the GLP-1 receptor, a protein that triggers hormones in the brain that keep the stomach full and tell the body to stop eating and avoid cravings.

A report published Wednesday by Trilliant Health found that prescriptions for the drug quadrupled from early 2020 to the end of next year, with providers writing more than nine million prescriptions in the last three months of 2022.  

The research is limited, but scientists also believe Ozempic can control the brain’s complex reward pathway that floods the brain with a rush of dopamine when something good happens, such as biting into a delicious cookie, and encourages you to eat more. 

This could potentially curb addictive behaviors, such as drinking alcohol, smoking, or even gambling. 

A study published in July in the journal eBioMedicine on mice measured the effects of semaglutide on alcohol consumption. 

The mice had previously been exposed to alcohol and had grown to enjoy it. During the study, they were allowed free reign of alcohol in addition to their food and water.

Rodents taking semaglutide consumed half the alcohol of those given a placebo.

Even when researchers took their alcohol away to give them stronger cravings, they still drank much less than the placebo group when the alcohol was made available again. 

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